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Hydrocodone is a pain medication used to manage moderate to severe pain by binding to opioid receptors in the brain and spinal cord . Hydrocodone has many types of variants like hydrocodone 10-325 mg ,hydrocodone 5-325 mg ,hydrocodone 10-500 mg It works by binding to opioid receptors in the brain and spinal cord, altering the way the body feels and responds to pain. Acetaminophen is a non-opioid pain reliever and fever reducer.