Hydrocodone acetaminophen 10-325 is a combination of two pain relievers: 10 mg hydrocodone and 325 mg acetaminophen. Hydrocodone is a narcotic analgesic. Acetaminophen is the active ingredient in Tylenol. Hydrocodone acetaminophen 5-325 is indicated for relieving moderate to severe pain. Brand names include Norco and Lortab.