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Methadone is a full opioid agonist.
It is also used in medication-assisted treatment (MAT) for opioid dependence, particularly for individuals with a history of opioid addiction.
Methadone works by binding to opioid receptors in the brain, producing similar effects to other opioids but with a longer duration of action.
Methadone helps to alleviate withdrawal symptoms and reduce cravings, allowing individuals to function normally without experiencing euphoria or impairment.
Methadone maintenance therapy involves daily doses of methadone, administered under medical supervision at specialized clinics.
Unlike Subutex, which can be prescribed by qualified healthcare providers in an office-based setting, methadone is typically dispensed through federally regulated opioid treatment programs (OTPs).
Methadone has a higher risk of dependence and overdose compared to buprenorphine, and strict monitoring and dose adjustments are necessary to minimize these risks.
Methadone maintenance therapy is often combined with counseling, support groups, and other psychosocial interventions to promote recovery and reduce the likelihood of relapse.

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