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Opana ER is a brand name for the extended-release formulation of the opioid medication oxymorphone. It is used to manage chronic, moderate to severe pain when continuous, around-the-clock opioid treatment is needed. Opana ER works by binding to opioid receptors in the brain and spinal cord, altering the perception of pain. It is available in tablet form and is designed to provide long-lasting pain relief, typically lasting for about 12 hours per dose. However, like other opioids, Opana ER carries a risk of misuse, dependence, addiction, and overdose. Therefore, it should only be used under the supervision of a healthcare professional and as prescribed. It's important to follow the prescribed dosage, avoid alcohol consumption while taking Opana ER, and never share the medication with others. Additionally, abrupt discontinuation of Opana ER can lead to withdrawal symptoms, so it's essential to taper off the medication gradually if it's no longer needed.